3-methylcyclotridecan-1-one
Basic Information
- CAS No.: 61415-11-0
Physical properties
Product Description
Export Top Purity 3-methylcyclotridecan-1-one 61415-11-0 In Stock
- Molecular Formula: C14H26O
- Molecular Weight: 210.36
- Vapor Pressure: 0.0014mmHg at 25°C
- Refractive Index: 1.437
- Boiling Point: 296.8 °C at 760 mmHg
- Flash Point: 125.7 °C
- PSA： 17.07000
- Density: 0.851 g/cm3
- LogP: 4.49630
3-methylcyclotridecan-1-one(Cas 61415-11-0) Usage
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General Description |
3-methylcyclotridecan-1-one, also known as muscone, is a naturally occurring fragrance compound found in the musk gland of musk deer. It is a macrocyclic ketone with a strong and long-lasting musky odor, often described as animalic, sweet, and powdery. Used in perfumery for its fixative properties, muscone is highly valued for its ability to enhance and prolong the scent of other fragrance ingredients. Due to its scarcity and ethical concerns related to musk deer farming, 3-methylcyclotridecan-1-one is mostly synthesized in the laboratory to meet the demand for musk-scented products. Despite its synthetic production, muscone remains one of the most widely used musk fragrances in the perfume and cosmetic industry. |
InChI:InChI=1/C14H26O/c1-13-10-8-6-4-2-3-5-7-9-11-14(15)12-13/h13H,2-12H2,1H3
61415-11-0 Relevant articles
Diradical-promoted (n + 2 - 1) ring expansion: An efficient reaction for the synthesis of macrocyclic ketones
Rueedi, Georg,Oberli, Matthias A.,Nagel, Matthias,Hansen, Hans-Jurgen
, p. 3179 - 3181 (2007/10/03)
(Chemical Equation Presented) A diradica...
Short and versatile two-carbon ring expansion reactions by thermo-isomerization: Novel straightforward synthesis of (±)-muscone, nor- and homomuscones, and further macrocyclic ketones
Nagel, Matthias,Hansen, Hans-Jürgen,Fráter, Georg
, p. 280 - 284 (2007/10/03)
Thermo-isomerization of 1-vinyl substitu...
Macrocyclic ring closure of OH-assisted Prins reaction. A new and efficient synthesis of (R, S)-muscone
Schulte-Elte,Hauser,Ohloff
, p. 2673 - 2680 (2007/10/10)
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61415-11-0 Process route
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2-(prop-1-enyl)-2-trimethylsilyloxycyclododecanone
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61415-11-0
dinormuscone
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2-methylcyclotetradecane-1,4-dione
| Conditions | Yield |
|---|---|
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2-(prop-1-enyl)-2-trimethylsilyloxycyclododecanone;
at 560 ℃;
under 0.015001 - 0.030002 Torr;
With
hydrogenchloride;
In
ethanol;
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71%
15% |
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2-hydroxy-2-(prop-1-enyl)cyclododecanone
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61415-11-0
dinormuscone
| Conditions | Yield |
|---|---|
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Multi-step reaction
with
2
steps
1.1: 99 percent / DMAP; Et3
N / dimethylformamide / 1 h / 20 °C
2.1: 560 °C / 0.02 - 0.03 Torr
2.2: 71 percent / HCl / ethanol
With
dmap; triethylamine;
In
N,N-dimethyl-formamide;
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61415-11-0 Upstream products
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73125-88-9
(Z)-12-Methyl-14-oxa-bicyclo[8.3.1]tetradeca-5,11-diene