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4-Bromophthalic acid
Basic Information
- CAS No.: 6968-28-1
Physical properties
Product Description
Manufacturer supply good quality 4-Bromophthalic acid 6968-28-1 with stock
- Molecular Formula: C8H5 Br O4
- Molecular Weight: 245.029
- Vapor Pressure: 1.54E-07mmHg at 25°C
- Melting Point: 162-164°C
- Refractive Index: 1.4490 (estimate)
- Boiling Point: 412.4oC at 760 mmHg
- PKA: 2.86±0.10(Predicted)
- Flash Point: 203.2oC
- PSA： 74.60000
- Density: 1.8281 (rough estimate)
- LogP: 1.84550
4-Bromophthalic acid(Cas 6968-28-1) Usage
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General Description |
4-Bromophthalic acid, also known as 4-bromobenzoic acid-2-carboxylic acid or simply 4-bromo-2-carboxybenzoic acid, is a chemical compound that falls under the category of organobromides and benzene and substituted derivatives. Its molecular formula is C8H5BrO4 and it exhibits a molar mass of 249.03 g·mol?1. This acid appears as a solid and is mainly used in the field of organic synthesis. It is known to be a brominated derivative of phthalic acid. Since it's a chemical substance, appropriate safety precautions should be ensured while handling it to prevent exposure and possible associated hazards. It's recommended to always use personal protective equipment, and to work in a well-ventilated space or with approved equipment. |
InChI:InChI=1/C8H5BrO4/c9-4-1-2-5(7(10)11)6(3-4)8(12)13/h1-3H,(H,10,11)(H,12,13)/p-2
6968-28-1 Relevant articles
Synthesis of 4-phenylethynylphthalic anhydride, a useful end-capping agent for polyimides
Yang, Mei-Jia,Shao, Tao,Men, Jian,Gao, Guo-Wei,Chen, Hua
, p. 379 - 380 (2012)
Hydrolysis and bromination of phthalic a...
CYCLIC PEPTIDE ANALOGS OF MELANOCORTIN AND AMANITIN AND METHODS OF MAKING SUCH
-
Paragraph 0114-0115; 0122, (2021/01/29)
The invention described herein is based ...
Fluorescent Isoindole Crosslink (FlICk) Chemistry: A Rapid, User-friendly Stapling Reaction
Todorovic, Mihajlo,Schwab, Katerina D.,Zeisler, Jutta,Zhang, Chengcheng,Bénard, Francois,Perrin, David M.
supporting information, p. 14120 - 14124 (2019/07/31)
The stabilization of peptide secondary s...
Synthesis and biological evaluation of chemokine receptor ligands with 2-benzazepine scaffold
Thum, Simone,Kokornaczyk, Artur K.,Seki, Tomoaki,De Maria, Monica,Ortiz Zacarias, Natalia V.,de Vries, Henk,Weiss, Christina,Koch, Michael,Schepmann, Dirk,Kitamura, Masato,Tschammer, Nuska,Heitman, Laura H.,Junker, Anna,Wünsch, Bernhard
supporting information, p. 401 - 413 (2017/05/04)
Targeting CCR2 and CCR5 receptors is con...
Industrial preparation method of 5-bromophthalide
-
Paragraph 0012; 0013; 0014; 0015; 0016, (2017/09/01)
The invention relates to a preparation m...
6968-28-1 Process route
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-
85-44-9
phthalic anhydride
-
-
6968-28-1
4-bromophthalic acid
| Conditions | Yield |
|---|---|
|
With
bromine; sodium hydroxide;
In
water;
for 72h;
Reflux;
|
95%
|
|
phthalic anhydride;
With
sodium hydroxide;
In
water;
at 40 - 95 ℃;
for 1h;
With
bromine;
In
water;
at 40 - 95 ℃;
Temperature;
Reagent/catalyst;
|
70.9%
|
|
phthalic anhydride;
With
bromine; sodium hydroxide;
In
water;
at 90 ℃;
for 7h;
With
hydrogenchloride;
In
water;
pH=Ca. 1.5;
|
68%
|
|
phthalic anhydride;
With
sodium hydroxide;
In
water;
With
bromine;
In
water;
at 90 ℃;
for 7h;
With
hydrogenchloride;
In
water;
|
68%
|
|
With
sodium hydroxide; bromine;
|
|
|
phthalic anhydride;
With
sodium hydroxide;
In
water;
With
bromine;
In
water;
at 20 - 90 ℃;
With
hydrogenchloride;
In
water;
|
|
|
Multi-step reaction
with
2
steps
1: sodium hydroxide; bromine / water / 7 h / 90 °C
2: hydrogenchloride / water
With
hydrogenchloride; bromine; sodium hydroxide;
In
water;
|
-
-
580-13-2
2-bromonaphthalene
-
-
6968-28-1
4-bromophthalic acid
| Conditions | Yield |
|---|---|
|
With
sodium hypochlorite; ruthenium(III) chloride trihydrate; sulfuric acid; tetrabutylammomium bromide;
In
water; 1,2-dichloro-ethane;
at 23 ℃;
for 0.333333h;
pH=9;
Green chemistry;
|
52%
|
6968-28-1 Upstream products
-
85-44-9
phthalic anhydride
-
14548-39-1
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-
16239-18-2
1,6-dibromo-2-naphthol
-
68837-59-2
4-bromo-2-methylbenzoic acid
6968-28-1 Downstream products
-
38568-41-1
diethyl 4-bromophthalate
-
19055-84-6
2-(4-Chlorphenyl)-5-brom-indandion-(1,3)
-
1470-35-5
5-bromo-2-phenyl-indan-1,3-dione
-
19055-83-5
5-Brom-2-(m-tolyl)-1,3-indandion