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3-Chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone

Basic Information

  • CAS No.: 41762-76-9

Physical properties

Product Description

Quality products?make an important contribution to long-term revenue and profitability. Factory Sells Best Quality 3-Chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone 41762-76-9 with steady supply

1.What is the 3-Chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone ?

Used in Pharmaceutical Industry:
3-Chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone is used as a coupling agent for the synthesis of peptides, facilitating the formation of amide bonds. Its efficiency and selectivity in bond formation contribute to the advancement of peptide-based drugs and therapeutics.
Used in Organic Synthesis:
In the field of organic synthesis, 3-Chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone is utilized as a reagent to selectively form amide bonds, which is crucial for the construction of complex organic molecules and the development of new chemical entities.
Used in Anti-tumor and Anti-inflammatory Applications:
3-Chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone has been reported to exhibit anti-tumor and anti-inflammatory activities, making it a potential candidate for use in cancer therapy and the treatment of inflammatory conditions. However, further research is needed to fully understand its therapeutic potential and safety profile.

phosgene
75-44-5

phosgene

1-(methylsulphonyl)-2-oxo-2,3,4,5-tetrahydroimidazole
41730-79-4

1-(methylsulphonyl)-2-oxo-2,3,4,5-tetrahydroimidazole

3-chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone
41762-76-9

3-chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone

Conditions
Conditions Yield
In 1,4-dioxane;
70%
In 1,4-dioxane;
70%
In 1,4-dioxane;
70%
In 1,4-dioxane;
70%
With chloro-trimethyl-silane; triethylamine; Yield given. Multistep reaction; 1.) dioxane, 3 d, reflux; 2.) room temp., overnight;
1-(methylsulphonyl)-2-oxo-2,3,4,5-tetrahydroimidazole
41730-79-4

1-(methylsulphonyl)-2-oxo-2,3,4,5-tetrahydroimidazole

trichloromethyl chloroformate
503-38-8

trichloromethyl chloroformate

3-chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone
41762-76-9

3-chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone

Conditions
Conditions Yield
With pyridine; In chloroform; at 50 - 55 ℃; for 3h;
85%

2.What is the CAS number for 3-Chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone ?

The CAS number of 3-Chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone is 41762-76-9.

More information of 3-Chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone 41762-76-9 are:

CAS?Number

41762-76-9

Density

1.71 g/cm3

Melting Point

168-173 °C(lit.)

Boiling Point

347.9 °C at 760 mmHg

Flash Point

164.2 °C

Vapor Pressure

5.21E-05mmHg at 25°C

Refractive Index

1.594

HS CODE

29332900

PSA

83.14000

LogP

0.99900

Pka

-2.60±0.20(Predicted)

3.What are another words for 3-Chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone ?

Synonyms?for?3-Chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone 41762-76-9:1-(Chlorocarbonyl)-3-mesyl-2-oxoimidazolidine;1-Chlorocarbonyl-3-methylsulfonylimidazolidin-2-one;3-(Methylsulfonyl)-2-oxoimidazolidine-1-carbonyl chloride;3-(Methylsulfonyl)imidazolidin-2-one-1-carbonyl chloride;3-Mesyl-2-oxo-1-imidazolidinecarbonyl chloride;

4.What is the molecular formula of 3-Chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone?

The chemical formula of ?3-Chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone is?C5H7ClN2O4S which containing 5 Carbon atoms,7 Hydrogen atoms,1 Chlorine atoms,2 Nitrogen atoms,4 Oxygen atoms and 1 Sulfur atoms,and the molecular weight of??3-Chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone?is 226.641.

5.What is 3-Chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone (41762-76-9) used for?

3-Chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone, also known as N-chloroacetyl-N-mesylimidazolidinone, is a chemical compound that serves as a versatile coupling agent in peptide synthesis. It is a white solid that is soluble in most organic solvents and remains stable under normal conditions. 3-Chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone is recognized for its efficient and selective formation of amide bonds without the need for condensation reagents, which makes it an invaluable asset in organic synthesis. Furthermore, it has demonstrated anti-tumor and anti-inflammatory properties, although its toxicity and environmental impact have not been extensively studied.

InChI:InChI=1/C5H7ClN2O4S/c1-13(11,12)8-3-2-7(4(6)9)5(8)10/h2-3H2,1H3

Relevant articles related to 3-Chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone:

Article

Source

The preparation of 3-substituted 1-chlorocarbonyl-imidazolidin-2-ones using bis(trichloromethyl) carbonate

Su,Zhang

, p. 440 - 441 (2007/10/03)

7-Ureido acetamido substituted cephalosporin antibiotics

-

, (2008/06/13)

6.Buy 3-Chlorocarbonyl-1-methanesulfonyl-2-imidazolidinone with the best price .

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