1-Butylpyrrolidine
Basic Information
- CAS No.: 767-10-2
Physical properties
Product Description
Manufacturers supply cost-effective and customizable 1-Butylpyrrolidine 767-10-2
- Molecular Formula: C8H17 N
- Molecular Weight: 127.23
- Vapor Pressure: 3.14mmHg at 25°C
- Refractive Index: n20/D 1.44(lit.)
- Boiling Point: 155-157 ºC (754 mmHg)
- Flash Point: 97 ºF
- PSA： 3.24000
- Density: 0.814
- LogP: 1.82020
1-Butylpyrrolidine(Cas 767-10-2) Usage
|
Preparation |
The synthesis of 1-butylpyrrolidine and its derivatives (1-butylpyrrolidine with a little of 1-butenylpyrrolidines) was developed via a one-pot method from ammonia and 1,4-butandiol. Here, the product of 1-butylpyrrolidine was emphatically investigated, and the yield was 76% under the optimized conditions. Such a route was realized through successive N-alkylation using aqueous ammonia as the nitrogen source over the CuNiPd/ZSM-5 catalyst, which was prepared by a simple incipient wetness method. In this route, 1,4-butandiol not only participated in the formation of the N-heterocycle, but also acted as an alkylating reagent. This work offers a straightforward, economical route for 1-butylpyrrolidine and its derivatives.One-pot synthesis of 1-butylpyrrolidine and its derivatives from aqueous ammonia and 1,4-butandiol over CuNiPd/ZSM-5 catalysts |
InChI:InChI=1/C8H17N/c1-2-3-6-9-7-4-5-8-9/h2-8H2,1H3
767-10-2 Relevant articles
Highly economical and direct amination of sp3carbon using low-cost nickel pincer catalyst
Brandt, Andrew,Rangumagar, Ambar B.,Szwedo, Peter,Wayland, Hunter A.,Parnell, Charlette M.,Munshi, Pradip,Ghosh, Anindya
, p. 1862 - 1874 (2021/01/20)
Developing more efficient routes to achi...
One-pot synthesis of 1-butylpyrrolidine and its derivatives from aqueous ammonia and 1,4-butandiol over CuNiPd/ZSM-5 catalysts
Long, Yan,Liu, Shimin,Ma, Xiangyuan,Lu, Liujin,He, Yude,Deng, Youquan
supporting information, p. 16708 - 16712 (2020/10/27)
The synthesis of 1-butylpyrrolidine and ...
Method for catalytically synthesizing 1-substituted pyrrolidine/piperidine derivative by using supported metal
-
Paragraph 0015; 0025; 0028-0030, (2020/02/20)
The invention provides a method for cata...
Combinatorial discovery of thermoresponsive cycloammonium ionic liquids
Chu, Yen-Ho,Hwang, Chun-Chieh,Chen, Chien-Yuan,Tseng, Min-Jen
supporting information, p. 11855 - 11858 (2020/10/13)
This work demonstrated, for the first ti...
767-10-2 Process route
-
-
110-63-4
Butane-1,4-diol
-
-
7335-07-1
N-propylpyrrolidine
-
-
767-10-2
1-butylpyrrolidine
-
-
71-36-3
butan-1-ol
| Conditions | Yield |
|---|---|
|
With
ammonium hydroxide; hydrogen;
at 300 ℃;
for 4h;
under 30003 - 75007.5 Torr;
Reagent/catalyst;
Autoclave;
|
72 %Chromat.
10 %Chromat. 14 %Chromat. |
-
-
110-63-4
Butane-1,4-diol
-
-
109-99-9,24979-97-3,77392-70-2
tetrahydrofuran
-
-
767-10-2
1-butylpyrrolidine
-
-
7255-63-2
1-(3-buten-1-yl)pyrrolidine
-
-
105-25-9
1-(2-buten-1-yl)pyrrolidine
-
-
71-36-3
butan-1-ol
| Conditions | Yield |
|---|---|
|
With
ammonium hydroxide; hydrogen;
at 300 ℃;
for 4h;
under 30003 - 75007.5 Torr;
Autoclave;
|
50 %Chromat.
7 %Chromat. 10 %Chromat. 20 %Chromat. 6 %Chromat. |
767-10-2 Upstream products
-
109-99-9
tetrahydrofuran
-
109-73-9
N-butylamine
-
123-75-1
pyrrolidine
-
109-65-9
1-bromo-butane
767-10-2 Downstream products
-
94-32-6
ethyl 4-(N-butylamino)benzoate
-
56511-17-2
1-n-Butyl-1-methylpyrrolidinium iodide
-
607-68-1
2,4-dichloroquinazoline
-
81683-46-7
4-chloro-2-(N-butyl-4-chlorobutylamino)quinazoline