1-(o-chlorophenyl)piperazine hydrochloride
Basic Information
- CAS No.:55974-33-9
Physical properties
Product Description
Factory Supply industrial standard 1-(o-chlorophenyl)piperazine hydrochloride 55974-33-9 In Stock
- Molecular Formula:C10H13ClN2*2ClH
- Molecular Weight:269.601
- Boiling Point:317.4°Cat760mmHg
- Flash Point:145.7°C
- PSA：15.27000
- Density:g/cm3
- LogP:2.94540
55974-33-9 Relevant articles
Design, synthesis and biological evaluation of 1-Aryl-5-(4-arylpiperazine-1-carbonyl)-1H-tetrazols as novel microtubule destabilizers
Wang, Chao,Li, Yuelin,Liu, Zi,Wang, Zeyu,Liu, Zihan,Man, Shuai,Zhang, Yujing,Bao, Kai,Wu, Yingliang,Guan, Qi,Zuo, Daiying,Zhang, Weige
, p. 549 - 560 (2021/02/05)
A series of 1-aryl-5-(4-arylpiperazine-1...
Preparation method of diaryl sulfide amine compound
-
Paragraph 0060-0062, (2020/03/12)
The invention relates to a preparation m...
Design, synthesis, and evaluation of bitopic arylpiperazine-phthalimides as selective dopamine D3 receptor agonists
Cao, Yongkai,Sun, Ningning,Zhang, Jiumei,Liu, Zhiguo,Tang, Yi-zhe,Wu, Zhengzhi,Kim, Kyeong-Man,Cheon, Seung Hoon
supporting information, p. 1457 - 1465 (2018/10/02)
The dopamine D3 receptor (D3R) is a prov...
POLY-ADP RIBOSE POLYMERASE (PARP) INHIBITORS
-
Page/Page column 45; 46, (2018/07/29)
The present invention is related to a ph...
55974-33-9 Process route
-
-
821-48-7
bis-(2-chloroethyl)amine hydrochloride
-
-
95-51-2
o-chloroaniline
-
-
41202-32-8,55974-33-9,76835-05-7
1-(2-chlorophenyl)piperazine hydrochloride
| Conditions | Yield |
|---|---|
|
With
sodium carbonate;
In
ethanol;
at 80 ℃;
for 25h;
|
96% |
|
In
sulfolane;
at 150 ℃;
for 14h;
|
90% |
|
With
2-(2-methoxyethoxy)ethyl alcohol;
at 150 ℃;
for 12h;
|
85% |
|
With
2-(2-methoxyethoxy)ethyl alcohol;
at 150 ℃;
for 12h;
|
85% |
|
In
diethylene glycol dimethyl ether;
at 130 ℃;
for 15h;
|
70% |
-
-
1104513-49-6
tert-butyl 4-(2-chlorophenyl)piperazine-1-carboxylate
-
-
41202-32-8,55974-33-9,76835-05-7
1-(2-chlorophenyl)piperazine hydrochloride
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride;
In
1,4-dioxane;
at 0 - 20 ℃;
for 4h;
|
84% |
55974-33-9 Upstream products
-
821-48-7
bis-(2-chloroethyl)amine hydrochloride
-
95-51-2
o-chloroaniline
-
1104513-49-6
tert-butyl 4-(2-chlorophenyl)piperazine-1-carboxylate
-
106-47-8
4-chloro-aniline
55974-33-9 Downstream products
-
95395-61-2
6-<2-<4-(2-chlorophenyl)-1-piperazinyl>ethyl>-5,6,7,8-tetrahydro-1,6-naphthyridine difumarate
-
83100-06-5
6-{3-[4-(2-Chloro-phenyl)-piperazin-1-yl]-propyl}-5,6,7,8-tetrahydro-[1,6]naphthyridine; compound with (E)-but-2-enedioic acid
-
870126-91-3
{2-amino-4-[4-(2-chlorophenyl)piperazino]-1,3,5-triazin-6-yl}acetonitrile
-
1061700-87-5
ethyl 4-[4-(2-chlorophenyl)piperazin-1-yl]butanoate